Incorporating Lion's Mane into a daily health regimen can encourage a more positive mood and a healthier outlook on life by supporting healthy brain function and neurotransmitter balance.
According to an animal study published in the Journal of Medicinal Food, Lion's Mane may support a healthy mood by promoting hippocampal neurogenesis [7]. The hippocampus is a brain region that plays an important role in emotional responses. Lion's Mane stimulated the expression of proteins involved in brain plasticity, which is crucial for maintaining a healthy mood.
These findings are supported by another study appearing in Biomedical Research, whereby supplementation with Lion's Mane was found to significantly promote a healthier outlook on life among menopausal women [8].
Given the increasing evidence supporting the gut-brain axis, it is possible that the benefits of Lion's Mane on mood may also be influenced by its gut-supporting properties.
The gut-brain axis is a fascinating system that connects your digestive tract and your brain, influencing your mood, cognition, immune system, and more.
Your gut is home to trillions of microbes, collectively known as the microbiome, that produce various molecules that can affect your brain function. These molecules can travel through the bloodstream, the nervous system, or the immune system, reaching different parts of the brain and altering its activity. For example, some gut bacteria can produce neurotransmitters, such as serotonin and dopamine, that regulate your emotions and motivation.
The gut-brain axis also works in reverse, meaning that your brain can influence your gut function. Your thoughts and feelings can trigger the release of hormones, such as cortisol and adrenaline, that affect your digestion and gut motility. Stress, anxiety, and depression can also alter the composition and diversity of your microbiome, leading to inflammation and dysbiosis.
So by supporting both the brain and the gut (discussed in detail below), Lion's Mane can have a positive impact on overall health and well-being.